Skincare Ingredients to Avoid: What’s Actually Worth Worrying About

Here’s something worth sitting with: the average person applies products containing around 126 unique chemical ingredients to their skin before breakfast. Not across the day. Before. (EWG)

Not all 126 matter. The vast majority are actually harmless. The issue is, we keep seeing the same short list of toxic chemicals appearing in peer-reviewed research, on regulatory restricted lists, and in ingredient safety databases, and that list is worth knowing.

This isn’t a throw-out-your-entire-bathroom situation. It’s a here’s-what-we-actually-found situation.

Why the US is playing catch-up

The FDA has banned or restricted only 11 cosmetic ingredients.. The European Union has restricted over 2,400! (Campaign for Safe Cosmetics, FDA prohibited ingredients)

That gap isn’t a clean beauty talking point that they want you to hear. Why is the gap so big though? The EU runs on a precautionary principle: credible evidence of harm means restriction, while the science catches up. The US waits for harm to be proven, which in practice means cosmetics brands operate with no pre-market safety review at all. They can formulate a product, put it in a bottle, and start selling it without the FDA signing off on anything.

It’s a 1938 framework that’s still running in 2026. Not a conspiracy. Just the regulatory reality.

What actually has evidence behind it

Every skin care ingredient below has peer-reviewed research against it, documented regulatory concern, or both. We’ve arranged them roughly by how much we’d personally prioritise them.

Parabens

Most people have heard of these by now. On the ingredient list, they can come in many different forms: Methylparaben, ethylparaben, propylparaben, butylparaben. They’re synthetic preservatives that keep products shelf-stable for years, and because they’re cheap and effective, they end up in everything from budget body lotions to premium serums.

They’re estrogen mimics, meaning they bind to estrogen receptors and can interfere with hormonal signalling. A 2004 study in the Journal of Applied Toxicology found intact parabens in 18 of 20 breast tumour tissue samples. (Darbre et al., 2004) Correlation, not causation. But the researchers were clear: they got in, they stayed in, and they were measurable in concentrations with biological activity.

They’re still legal in the US and widely used across every price bracket. On labels, look for anything ending in -paraben.

Phthalates

These are sneaky in a way parabens aren’t. Phthalates are plasticisers that help fragrance last and give products a certain texture, but they often don’t show up on the label by name. They hide inside the word “fragrance,” a legal catch-all that companies don’t have to break down because fragrance blends are protected as trade secrets under US labelling law. Pretty convenient that a company’s “proprietary formula” can hide ingredients that people are actively seeking to avoid.

So when you see “fragrance” or “parfum” on a label, you’re looking at a black box. Could be completely harmless. Could contain dibutyl phthalate, diethyl phthalate, and several other compounds linked to hormone disruption, reproductive harm, and developmental issues in children. No way to know without calling the company directly.

The EU restricts several phthalates in cosmetics. The FDA hasn’t followed. If you want to minimise exposure, “fragrance-free” on the label (the actual INCI term, not “unscented”) is what you’re looking for.

Formaldehyde (and the ingredients that release it)

Formaldehyde in cosmetics usually doesn’t say formaldehyde. It shows up as preservatives that release it slowly over the product’s shelf life: DMDM hydantoin, quaternium-15, imidazolidinyl urea, diazolidinyl urea. These are common in shampoos, conditioners, and body washes. Most people scan straight past them.

Formaldehyde is a Group 1 human carcinogen (meaning it has the potential to cause cancer), classified as such by both the International Agency for Research on Cancer and the US National Toxicology Program. (IARC classifications) The EU has significant restrictions on its concentration in cosmetics. In the US, there’s no cap for leave-on products. Keratin hair treatments are a specific hotspot because heat accelerates formaldehyde release during application.

“Fragrance” as its own problem

We already covered fragrance under phthalates, but it needs more space because it’s one of the most common triggers for skin reactions and most people never connect the two.

The word “fragrance” on an ingredient list can legally represent anywhere from a handful to hundreds of undisclosed chemicals. That labelling law dates from 1966 and hasn’t been meaningfully updated. If your skin reacts to products for no obvious reason, redness, irritation, random breakouts, fragrance is statistically the most likely culprit, and you’d have no way of knowing because it’s not itemised.

If you’re going to cut one category from your routine, synthetic fragrance in leave-on products is where to start.

Oxybenzone

Hawaii banned sunscreens containing oxybenzone from sale near protected marine areas. Not for the story, because it actually damages coral reefs at measurable concentrations. That’s the environmental side. On the human health side, a 2019 study in JAMA found measurable oxybenzone levels in blood plasma after just one day of application. (Matta et al., JAMA 2019) At certain concentrations it functions as an endocrine disruptor. The FDA proposed reviewing its “generally recognised as safe” status in 2019. That review hasn’t been finalised.

Zinc oxide and titanium dioxide are the mineral alternatives. Modern mineral formulas have caught up considerably. Most no longer leave a visible white cast on mid-to-deep skin tones.

Sulfates (SLS and SLES)

Honestly, this is the least alarming item on the list. Sodium lauryl sulfate and sodium laureth sulfate are the surfactants that make cleanser foam. They work fine. For a lot of people with dry, sensitive, or eczema-prone skin they’re also irritating, because they strip natural oils.

There’s a secondary thing worth knowing: during manufacturing, SLES can be contaminated with 1,4-dioxane, a probable carcinogen flagged by both the EPA and FDA. It won’t appear on the label because it’s a manufacturing byproduct, not an added ingredient.

If your skin is happy with your current cleanser, you’re probably fine. If it reacts to every foaming product you try, cutting sulfates is a sensible first test.

PFAS (the one we’d actually lose sleep over)

In 2021, researchers at the University of Notre Dame tested 231 cosmetic products and found PFAS, the so-called “forever chemicals,” in more than half of waterproof and long-lasting formulas. Waterproof mascara. Long-wear foundation. Setting spray. (Whitehead et al., Environmental Science & Technology Letters, 2021)

PFAS don’t break down in the body or the environment. They accumulate. They’ve been connected to thyroid disruption, immune effects, and elevated cancer risk, and there’s no established safe exposure threshold because researchers are still working out what chronic low-level exposure does over decades.

This isn’t precautionary. The evidence trail on PFAS is long enough to warrant active avoidance. Check labels for PTFE or any ingredient with “fluoro” in the name. For waterproof products with no ingredient disclosure, look for brands that explicitly state PFAS-free.

The numbers, with context

A few stats that circulate on this topic are worth unpacking properly.

The 11 vs 2,400+ comparison (US bans vs EU restrictions) gets cited constantly. What it means in practice: EU consumers have been operating in a meaningfully different regulatory environment for decades. Products reformulated for European markets are often cleaner than their US equivalents sold under the same brand name. (Campaign for Safe Cosmetics, FDA) Not always. But often enough that it’s worth knowing.

The 126 daily chemical ingredients figure from EWG comes from adding up the unique ingredients across the average personal care routine. (EWG Skin Deep) The cumulative exposure question, what happens when you absorb several low-level hormone disruptors simultaneously every day for 40 years, is genuinely unresolved. Not a green light. An honest acknowledgement of where the science is.

EWG also estimates that 1 in 8 of the 82,000 ingredients used across personal care products are dangerous chemicals, industrial chemicals, harmful chemicals, including carcinogens, pesticides, and reproductive toxins. (EWG) That’s not 1 in 8 products. It’s the ingredient pool being broader and less regulated than most people picture when they imagine what goes into a moisturiser.

How to read a label without it taking forever

Ingredient lists are written in INCI, International Nomenclature of Cosmetic Ingredients, which is why glycerin says “glycerol” and water says “aqua.” That’s just a standardised naming system. The ingredients themselves aren’t more alarming because they’re in Latin.

What you should be scanning for:

  • “Fragrance,” “parfum,” or “aroma.” These are your first stop. If you have reactive skin or are pregnant, avoiding them in leave-on products is worth doing.
  • Anything ending in -paraben. Methylparaben, propylparaben, ethylparaben, butylparaben. Any of these means the product contains parabens.
  • The formaldehyde releasers: DMDM hydantoin, quaternium-15, imidazolidinyl urea, diazolidinyl urea. They won’t say formaldehyde. Those four names are what you’re looking for.
  • PTFE or anything with “fluoro” in the name, especially in waterproof or long-wearing products.

EWG’s Skin Deep database (ewg.org/skindeep) is free, searchable, and rates ingredients on a hazard scale of 1 to 10. Its methodology isn’t flawless — it sometimes conflates high concentration hazards with low-dose everyday use — but for a quick check it’s the most accessible independent tool available.

One more thing worth saying: a $100 face cream can contain the same parabens as a drugstore moisturiser. Price is not a proxy for ingredient safety. At all!!

On the word “natural”

You may see this on the packaging and assume that you’re safe… Wrong! “Natural,” “clean,” “green,” “non-toxic,” “pure” have no legal definitions under US cosmetics law. Any brand can print any of those words on any product, no standards required.

“Dermatologist-tested” means a dermatologist was involved at some point, not like they received the products that’s on the market and tested it under heavy standards. “Hypoallergenic” has no regulatory definition either.

The ingredient list is the only honest part of the label. Everything else is copywriting.

Where to actually start

Five specific things, if you want them:

  1. Your daily moisturiser first. It goes on a large surface area, repeatedly, often for years at a time. Scan for -paraben suffixes, the word fragrance, and the four formaldehyde releasers listed above. If it’s clean, move on. If not, that’s your first swap.
  2. Sunscreen for oxybenzone specifically. If it’s in the ingredient list, a zinc oxide or titanium dioxide formula is a straight upgrade. Modern mineral SPFs have come a long way on texture.
  3. Two products on EWG Skin Deep. Not the whole bathroom. Two. See what scores come back. Go from there.
  4. If you’re pregnant or trying to be: move parabens and phthalates to the top of your list. Endocrine disruption during foetal development is where the research is most consistent and most concerning.
  5. Swap as products run out, not all at once. Sudden full-routine changes are expensive, and skin that’s used to what it’s used to doesn’t always respond well. One replacement at a time is plenty.

What you do with this

US cosmetics regulation hasn’t been meaningfully updated since 1938. That’s not a conspiracy theory, it’s a fact with a timestamp, and individual purchasing decisions won’t change it at a structural level.

But knowing which specific ingredients have real evidence against them, parabens, phthalates, formaldehyde releasers, PFAS, fragrance as a catch-all, gives you something to work with when you’re actually standing in a shop or reading a product page. That matters. Click here, If you want to learn more about these harmful chemicals and their impact on your body’s endocrine system.

The moment you begin shopping mindfully with an awareness of these ingredients and tactics, you’ll soon realize that most things in the store are riddled with these things. Although these may be the most convenient solutions, you may be paying for it in other ways, and it won’t always be immediate. In my opinion, taking the extra time to do your research or paying a slight premium for a clean product is worth it if helps prevent health complications in the future. Given all the research that’s so easily accessible on these ingredients, I find it difficult to believe that company’s are unaware of these risks. Because of that, I sure don’t want to give them my money!

Your routine doesn’t need to be perfect. It just needs to be a bit more informed than it was before you read this.